Entourage Explorer
Filter by cannabinoids, terpenes and flavonoids to surface evidence-based combinations with rationale — your interactive tool for the entourage effect.
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21 combinations
Myrcene amplifies THC's sedative axis; caryophyllene binds CB2 and softens anxiety; cannflavin A adds anti-inflammatory action.
Linalool and CBD share anxiolytic pathways; pinene sharpens focus; quercetin stabilises CBD plasma levels via CYP modulation.
CBG, the 'stem-cell' cannabinoid, pairs with pinene's antibacterial action and cannflavin C as a rare cannabis-specific flavonoid.
CBN forms from THC oxidation and is sedative; myrcene and linalool deepen sleep, apigenin binds GABA receptors.
CBC modulates TRPA1/TRPV1; humulene and luteolin amplify peripheral anti-inflammatory action.
THCV suppresses appetite and energises; terpinolene and limonene support the clear-headed effect.
Raw-cannabis THCA is anti-inflammatory; pinene and cannflavin A reinforce the non-psychoactive cluster.
CBDA inhibits COX-2; linalool and cannflavin B complement the anti-inflammatory mechanism.
Myrcene dominates classic indicas and deepens the THC/CBN sedation axis.
Limonene lifts mood and pairs with THC/THCV in sativa chemovars; quercetin supports bioavailability.
β-caryophyllene is the only terpene that binds CB2 — direct synergy with THC and CBC.
α-pinene sharpens focus and softens THC-induced memory dulling; pairs with CBD/CBG-dominant flowers.
Linalool is anxiolytic and sedative; with CBD/CBN it forms the classic night profile.
Humulene suppresses appetite and is antibacterial; amplifies CBC's peripheral anti-inflammatory profile.
Terpinolene shapes clear-headed sativas; harmonises with THCV/CBG for active daytime use.
Cannflavin A is 30× more anti-inflammatory than aspirin (in vitro) and typical in THC-dominant chemovars.
Cannflavin B shares anti-inflammatory mechanisms with CBDA and enriches in CBD-rich chemovars.
Cannflavin C is a rare cannabis-specific flavonoid frequently present in CBG chemovars.
Quercetin modulates CYP enzymes, shifting the half-life of CBD and THCV.
Apigenin binds GABA receptors and reinforces the sedative THC/CBN cluster with myrcene/linalool.
Luteolin inhibits mast cells and completes CBC + β-caryophyllene in the peripheral anti-inflammatory cluster.